International Association for the Study of Pain®    IASP Press®
Progress in Pain Research and Management, Volume 17

Editor: Roger B. Fillingim, PhD

2000  :  hardbound :  416 pages  :  ISBN 0-931092-35-3  :  US$79.00  (IASP members US$55.00) 

Table of Contents                             Order Form                              Reviews                                   IASP

Providers of pain treatment as well as both basic and clinical scientists are alerted in this volume to the potential importance of sex-related factors in the experience of pain. A better understanding of the differences between the sexes will ultimately enhance our ability to diagnose and treat pain disorders of all types. This book provides a single resource summarizing many of the most important findings regarding sex, gender, and pain. Its contributors are leading international experts in this field whose perspectives include basic neuroscience, human laboratory research, clinical investigation, and epidemiological studies.

Table of Contents:

Part I Basic Considerations for Sex, Gender, and Pain Research

1.  Sex, Gender, and Pain: A Biopsychosocial Framework. Roger B. Fillingim
2.  Sensory Effects of Gonadal Hormones. Anna Maria Aloisi
3.  Interactions between Sex and Genotype in the Mediation and Modulation of Nociception in Rodents.
     Jeffrey  S. Mogil
4.  Psychosocial Contributions to Sex-Related Differences in Pain Responses.
Michael E. Robinson,
    Joseph L. Riley III, and Cynthia D. Myers

Part II Sex-Related Differences in Experimental Pain Responses

5.  Experimental Studies of Sex-Related Factors Influencing Nociceptive Responses: Nonhuman Animal 
     Research. Wendy F. Sternberg and Melissa W. Wachterman
6.  Ovarian Sex Steroids Activate Antinociceptive Systems and Reveal Gender-Specific Mechanisms. 
     Alan R. Gintzler and Nai-Jiang Liu
7.  How Does Vaginal Stimulation Produce Pleasure, Pain, and Analgesia? Barry R. Komisaruk and 
     Beverly Whipple
8.  Sex-Related and Hormonal Modulation of Visceral Pain. Maria Adele Giamberardino
9.  Sex and Gender Differences in Responses to Experimentally Induced Pain in Humans. Gary B. 
     Rollman, Stefan Lautenbacher, and Kevin S. Jones
10. The Influence of Menstrual Cycle and Sex Hormones on Pain Responses in Humans.
Roger B. 
      Fillingim and Timothy J. Ness
11. Sex-Related Differences in Analgesic Responses.
Christine Miaskowski, Robert W. Gear, and Jon 
      D. Levine

Part III Sex-Related Factors in Clinical Pain Conditions

12.  Epidemiologic Perspectives on Sex Differences in Pain. Linda LeResche
13.  Sex Differences in Recurrent Headache Disorders: Overview and Significance. Kenneth A. Holroyd 
      and Gay L. Lipchik
14.  Sex-Related Influences in Fibromyalgia. Laurence A. Bradley and Graciela S. Alarcón
15.  Sex-Related Factors in Temporomandibular Disorders. Roger B. Fillingim and William Maixner
16.  Sex and Gender in Irritable Bowel Syndrome. Bruce D. Naliboff, Margaret M. Heitkemper, Lin Chang, and 
       Emeran A. Mayer
17.  Female Genital Pain.
R. William Stones

Part IV Conclusions

18.  Female Pain Versus Male Pain? Karen J. Berkley


[This edited volume] is a seminal work as the first book to provide an in-depth discussion about the role of sex and gender in the pain experience. Many of the authors are members of the International Association for the Study of Pain Special Interest Group on Sex, Gender, and Pain. They are well-respected researchers who have contributed extensively to this area of research and practice.
    Basic science and experimental, clinical, and epidemiological research are given equal place in this book; research from one area frequently provides some insight into the complexity of the sex and gender issues discussed in another chapter … [The concluding chapter] draws out the interrelationships of these areas of research and the important contributions likely to be gleaned from concerted efforts to combine areas to address sex and gender aspects of pain experience.
    In sum, this book is an extremely helpful and essential resource for any researcher or clinician with an interest in sex, gender, and pain experience.
APA Review of Books (American Psychological Association)

This excellent book is another in the series from the International Association for the Study of Pain (IASP) Press on Progress in Pain [Pain Research and Management]. It fulfills the mission statement of the organization in that it provides a timely, high quality, low cost publication about a current pain problem. During the 1990s, there has been increased interest in the influence of sex and gender on pain. There have been National Institute of health initiatives and conferences about this important topic. There is now an IASP special interest group on sex, gender and pain.
Roger Fillingim, who is a recognized expert in the field, edits this book. The text brings together basic scientists and clinicians who explore the mechanisms and clinical importance of sex and gender differences in pain. There is something in this book to interest everyone. The text asks as many questions as it answers and gives many ideas for future research. The multi-factorial nature of the influence of sex and gender on pain is a recurrent theme, which involves the interaction of biological and psychological factors.
The [final chapter by Karen Berkley] provided an excellent summary of current knowledge and ideas for the future. This book is a must have for all departments and individuals involved in the study and management of pain. It supports the notion that men may be from Mars and women may be from Venus after all! 
British Journal of Anaesthesia

    In this work, a number of internationally renowned specialists provide an overview of the current knowledge regarding the multidimensional phenomenon of pain. As the title indicates, this book investigates the relationship of pain to gender based on the most recent basic, clinical, and epidemiological research. Today we know that men and women react differently to nociceptive stimuli and analgesic interventions. In other words, the perception of pain is not the same between the two sexes. A better understanding of these differences can [allow] doctors to diagnose and treat painful pathologies more efficiently. That is the intention of this book. De agenda Gynecologie/L’agende gynécologie

    This edited volume contains 18 chapters that summarize findings from a wide range of clinical and experimental studies on the relationships among sex, gender, and pain. The chapters are written by an impressive international group of experts and are consistently thorough and well-written, as well as understandable to readers unfamiliar with the area of research.
The first chapter, written by Roger Fillingim, provides a concise summary of the relevant historical effects preceding the publication of this book and an overview of the important issues covered in the book [ ]. The other chapters in this section are provocative and suggest interesting directions for future research.
A chapter on epidemiological perspectives provides a very useful table summarizing gender prevalence ratios found in different studies for a variety of pain conditions; this table nicely illustrates the female predominance across conditions as well as the variability in findings across studies. This chapter also points out the complex interactions among gender, age, and pain condition.
[Karen Berkley’s chapter, "Female Pain Versus Male Pain?" ...] provides a useful summary for the entire volume, illustrates how basic and clinical research can inform each other, and suggests a framework for future research in the area.
I believe this book deserves a place on the bookshelf of evry pain researcher, basic or clinical. It provides a thorough, comprehensive, and up-to-date review of this important topic. Reading (or even skimming through) this volume should heighten the sensitivity of every researcher to the importance of attention to sex- and gender-related issues in pain studies, as well as the importance of continued integration of basic and clinical research. APS Bulletin

2000  :  hardbound :  416 pages  :  ISBN 0-931092-35-3  :  US$79.00  (IASP members US$55.00)

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This page was updated on January 12, 2003